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Reply to "Measles Outbreak "
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[quote=Anonymous] PPS: More specifically, SSPE is a sequelae of infection with a strain of measles virus that contains the PEA motif (residues P64, E89, and especially A209) in the matrix protein. 9 out of the 10 gene sequenced wild-type measles virus strains contain that PEA motif, but the vaccine strains do not. The vaccine strains have an SKT motif (S64, K89, T209) instead. Measles viruses with the SKT motif have never been isolated in cases of SSPE, and neither has the one wild-type strain which does not have the PEA motif (i.e., genotype B3 with PET). So I'm not likely to concede that you are going to be killing a certain number of children a year via SSPE by giving them the measles vaccine. I would, however, like to be accurate in the predictions of how many would be likely to die from complications of measles infection, and for that I would first look at your reference for the number you gave. [/quote]
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