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[quote=Anonymous] PS: While I'm waiting to hear back from you on that, here is the most useful current article on SSPE, from the July 2025 edition of [i]Seminars in Pediatric Neurology[/i], https://pubmed.ncbi.nlm.nih.gov/40701692/ : [quote][b]Epidemiology[/b] ... The persistence of measles outbreaks in resource-limited settings ensures a continuous reservoir of SSPE cases, further burdening the fragile healthcare systems. [u]The global incidence of SSPE is estimated at 4-11 cases per 100,000 measles cases, and is higher in countries with a higher incidence of measles (up to 27.9 cases per 100,000 measles cases).[/u] ... Infants, particularly those under 12 months of age, are at a higher risk, with the likelihood of developing SSPE rising to 18 cases per 100,000 children. ... [u]The unfounded belief that the measles vaccine can cause or accelerate SSPE needs to be broken, as to date the vaccine virus has not been isolated from SSPE cases.[/u] While the re-emergence of SSPE in HIC is related to the measles outbreaks, many children with SSPE in LMIC have no history of prior measles infection. This is due to either a subclinical measles or undiagnosed mild measles infection during early childhood before vaccination.[/quote] [/quote]
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