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Reply to "is RKFJr's "Tylenol(TM) causes autism" just a shakedown for extortion money from the company? "
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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]Tylenol is about the only medicine that pregnant women have been allowed to take for decades. So that’s like saying tap water causes Autism. Because nearly every woman has taken Tylenol during pregnancy. Also, studies debunked it. [/quote] This is an area near and dear to my heart. I am aware that this is not the scientific consensus, but I am aware of no studies that “debunk[]” it. Can you identify them or at least share the basis of your statement?[/quote] This was referenced earlier in the thread. Very famously, the Swedes did a massive nationwide cohort study with sibling control analysis included a population-based sample of about 2.5 million children born in 1995 to 2019 in Sweden, with follow-up through December 31, 2021. [quote][b]Acetaminophen Use During Pregnancy and Children’s Risk of Autism, ADHD, and Intellectual Disability[/b] Viktor H. Ahlqvist, PhD; Hugo Sjöqvist, MSc; Christina Dalman, MD, PhD et al JAMA, Published Online: April 9, 2024. 2024;331;(14):1205-1214. Acetaminophen use during pregnancy was not associated with children’s risk of autism, ADHD, or intellectual disability in sibling control analysis. This suggests that associations observed in other models may have been attributable to familial confounding. https://jamanetwork.com/journals/jama/fullarticle/2817406[/quote] It is well known in the literature. Anyone who has looked into the question at even a superficial level knows about it; there is no way RFKJ is not being disingenuous. [/quote] Same PP. Also see: [quote] https://pubmed.ncbi.nlm.nih.gov/39637384/ , (meta-analysis of 56 studies, commentaries, and editorials) [b]Acetaminophen in Pregnancy and Attention-Deficit and Hyperactivity Disorder and Autism Spectrum Disorder[/b] Per Damkier, Erika B Gram, Michael Ceulemans, et al [i]Obstet Gynecol[/i]. 2025 Feb 1;145(2):168-176. doi: 10.1097/AOG.0000000000005802. Epub 2024 Dec 5. This suggests that residual confounding from shared genetic and environmental factors may have caused an upward bias in the original observations. According to the current scientific evidence, in utero exposure to acetaminophen is unlikely to confer a clinically important increased risk of childhood ADHD or ASD. The current level of evidence does not warrant changes to clinical guidelines on the treatment of fever or pain in pregnancy.[/quote] [/quote]
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