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Reply to "Intubated ventilator in Coronavirus patients. Soultion or problem. Why not to use unintubated?"
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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]My brother's a pulmonologist in CA treating COVID patients. He said in their general exprience, folks who need ventilators due to pneumonia caused by typical influenza or other common causes recover about 80% of the time. But with COVID, it's flipped, at they have seen 80% who need a ventilator end up dying. [/quote] Does your brother have a theory?[/quote] In general terms, [b]"something" happens in some people that triggers an often fatal immune response. [/b]He doesn't seem to have theories about what, specifically. Which is what worries him. Initially based on early reporting, he was pretty laid back about this all. But as more stats are out and now he's seeing things first-hand, he's very concerned. Yes, many of those who die are "high risk." But then there are enough relatively young people without known issues who have this response, too and end up dying.[/quote] I am sure he is familiar with the 2019 Novel Coronavirus and [b]Cytokine Storm[/b] https://lab-a-porter.com/2020/02/wuhan-coronavirus-and-cytokine-storm/ . This “cytokine storm” can trigger a viral sepsis in coronavirus infection, where viral replication and excessive, uncontrolled systemic inflammation can lead to pneumonitis, acute respiratory distress syndrome, respiratory failure, shock, organ failure, secondary bacterial pneumonia, and potentially death. This same correlation between cytokine storm and severity of illness was observed previously in both SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome) patients. The 2019-nCoV has a possible asymptomatic incubation period for up to 2 weeks, though who were infected often experience dry cough and fatigue. While the carrier can transmit the virus to others during this incubation, fever and the development of viral pneumonia follows.[/quote]
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