Reply to Will Ozempic and other drugs like it eliminate obesity?

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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymou[i]s][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]Why don’t you just eat less? More raw fruits and veggies. Pound a glass of water first and see if that fills you up.

I hate most unseasoned veggies so if I’m eating them, it’s because I’m actually hungry. A small amount fills me up.

You just have to get over the idea that food should bring you pleasure.[/quote]

LOL

“You should just get over your biological wiring that has evolved over millions of years to seek out food that tastes good”

Honestly how can some people be so stupid? [/quote]

Why the name calling? Why do you care that many of us on this thread are able to overcome whatever (wiring or laziness or whatever) and maintain a healthy weight? No one cares that you are obese and want to take a drug to lose weight. There are plenty of healthy, low calorie foods that taste good. When I was having a health issue I went to a provider who advised that I eat and move like my geat grandmother. That generation did not eat processed food or lead sedentary lifestyles. Once I made the changes the health issue disappeared. It wasn't easy and it cost more money and took longer than take out, but I didn't want to take the medicine.

Good luck to you.[/quote]

I’m very glad you are able to maintain a happy weight without pharmaceutical or surgical intervention. Love that for you. Unfortunately, many many people aren’t. To say that it’s as simple as eating less and moving more is asinine. If it was so simple, nearly half of people in our country wouldn’t be obese. [/quote]

Approximately 10 percent of U.S. adults were classified as having obesity during the 1950s. Today it is over 41 percent. Do you think lifestyle choices such as big gulps, fast food, driving vs walking, desk jobs, and watching TV has anything to do with the increase? What has changed? Why was 90 percent of the population a healthy weight then?[/quote]

You’re sooo close to the point. Telling people to eat less and move more does not fix any of the above. It also doesn’t help people be less fat. So we can either overhaul society and fix the current food and lifestyle environment (not likely) or encourage the use of tools like Ozempic etc to help people achieve and maintain a healthy weight in our current environment. [/quote]

Telling people may not help, but making lifestyle changes does help.

These are comments from someone taking Ozempic:

“I just kept gaining weight. I couldn’t lose it no matter what I did. I could eat salads for months, still couldn’t lose it.” “It was a constant struggle.”

K, who is prediabetic, found out her health insurance does cover Ozempic.

She began treatment in August 2021 and has lost 50 pounds since — 40 of which she attributes to the drug. She injects herself once a week in her stomach and describes the medicine’s effect as making her feel fuller faster.

“My complete diet has changed. I used to be able to eat a whole pizza and be completely fine and get it down. Now, if I try to get down like two slices, I feel completely sick. It’s too much grease. Greasy food in general is really hard for me,”

It's great that science and medicine are advancing and these drugs are available AND we need to overhaul society by getting people to understand it's best to eat one slice of pizza along with other filling, but not high calorie foods instead of the entire pizza or other greasy food and understand that it takes time to see the changes. More people have successfully lost and maintained with lifestyle changes than these drugs that's why I don't get the posters who insist that suggesting different food choices and more movement is judging or shaming.

[/quote]

Omg, how are you not getting this? You understand that without the Ozempic, two slices wouldn’t fill her up right? She was still really hungry after just two pieces. She knew it was best not to eat a whole pizza before, she isn’t a moron, but she was hungry and it’s not sustainable for most people to be hungry day in and day out long term. Her body wanted the calories it needed to support her weight, whatever it was, and her hunger reflected that. She couldn’t implement the lifestyle changes without the drug. [/quote]

DP. This is interesting. More and more we are witnessing disclosures about overweight people in fact eating more ("are more hungry"), than others. In the past, almost by default we'd hear in RL and most posts on this forum, that they don't really eat that much; it's was often explained by genetics or/and some undiagnosed condition. 
[/quote]

I think this is a good question that I am also trying to understand.  If you are overweight/obese (before taking drugs), is it because:

1) You eat primarily healthy food but are still hungry, so you end up eating large quantities.  And that made you gain weight.

2) You eat some healthy food but are still hungry, so you round it out with eating some fattening/unhealthy foods.

3) You are constantly hungry and basically eat whatever you want, as much as you want.

I'm trying to understand what the drug does to fix this.  Does it make you less hungry for all foods?  Does it make healthy foods seem more appealing than pizza and ice cream?

[B]I have always been average weight and I find it almost impossible to eat if I am not hungry.  Like, if there is an office party in the afternoon and I am still full from lunch, I can barely get a slice of cake down even if I really want to.  [/b]I also have an aversion to overly sweet foods (they make my teeth hurt) so naturally don't eat desserts.[/quote]

I am the PP with the (formerly) obese friend who has had great success with Wegovy. You are responding to one of the useless obnoxious posters in this thread, but your questions seem genuine so I will share my observations.

Prior to Wegovy, I don’t think my friend was ever full. What you describe in the bolded, I don’t think she ever felt. I’ve felt it, and I know what you mean, but she was never satiated. She could always eat more. I’ve been friends for many many years, and I’m convinced there is something deeply physiologically different with our bodies. If we went to dinner, I wouldn’t want dessert because I was too full, but she would want dessert but make herself refuse it for health reasons (she rarely eats dessert). So while I had the advantage of feeling satiated, she never felt “full” no matter how much she ate. Interestingly you didn’t list what I think was her reality in your numbered list: she was never satiated, so kept eating a lot of mostly healthy food. In other words a mix of all your numbers, but I think the key is that while I could eat a reasonable amount of healthy food and feel full, she could not. I don’t think you understand just how profound your advantage is with the bolded as far as weight control.

With Wegovy, she feels full for literally the first time since she was a child. She eats basically like I do now. She leaves food on her plate, and is uninterested in eating again for several hours after dinner (not the case before). She had a short period where she went off the drug because of supply chain issues and what she told me was that the feeling of never being satiated and of always being hungry came back.

In terms of foods, the drugs have made certain foods entirely unappetizing. She does not like dense proteins like red meat, and can only have a few bites if she has them. She doesn’t eat a lot of sweets. My friend can’t stand the taste of alcohol at all any more, though she was never a heavy drinker. I would say that she tends to make and eat soups, salads, tofu, and softer less dense proteins (cheeses as opposed to meats, fish instead of red meat). It seems like a pretty sustainable and healthy diet to me. When we have gone out to dinner together now, she orders appetizers for her main course because she gets full. Usually it’s something like a side salad with a cup of soup or something like that. No bread, that fills her up immediately.

I hope this helps explain a little. [/quote]

PP here.  Thank you, this is really interesting.  What is it about the drug, I wonder, that changed her body to feel fullness for the first time?  It does kind of give me a different view of obesity as a disease.  I think it's amazing that modern medicine can restore the way hunger functions in the body.[/quote]

My layman’s understanding is that this class of drugs works by driving the body to increase the amount of insulin produced by the pancreas, which is something that has long been documented as deficient in most obese people. It also slows down gastric motility, leading to the sensation of fullness or satiation.

It is pretty amazing science IMO. I also don’t think we have begun to scratch the surface on our understanding of obesity as a disease. 
[/quote]

It’s interesting, because many people who are overweight are insulin resistant, so their pancreas actually makes too MUCH insulin and they have extremely high insulin levels (at least early on, before the pancreas burns out and they become diabetic). So it doesn’t make sense that the drug stimulating the pancreas leads to weight loss. I think it’s really not fully understood how it works for weight loss, besides the delayed gastric emptying effect. [/quote]

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