Reply to SN “Believers” vs SN “Non-Believers” - how to do what is in the best interest of a child

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Reply to "SN “Believers” vs SN “Non-Believers” - how to do what is in the best interest of a child"

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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote] ADHD is a biologically-based difference rooted in brain chemistry and development. [/quote]

This is NOT TRUE. We spent a ton of time and money trying to prove it and we have no evidence at all for “brain chemistry” as a cause of ADHD. [/quote]

In fact, there is quite a lot of evidence for brain chemistry as one cause (among many causes) of attention disorder. Here is just one 2025 paper that sums up the multi-factoral causes:

“ Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent neurodevelopmental conditions worldwide, with an onset typically in childhood and frequent persistence into adulthood. Despite its high prevalence, t[b]he precise mechanisms underpinning ADHD remain elusive, largely due to its heterogeneity and complex interplay between neurobiological, genetic, and environmental factors. [/b]Recent publications have begun to shed light on these processes, offering critical insights into the neurochemical substrates, brain network dysfunctions, and psychosocial modulators that converge in ADHD and related psychiatric conditions.

A pivotal contribution comes from the study of glutamate imbalance in key structures of the default mode network (DMN) in adults with ADHD [1]. This work demonstrates that excitatory neurotransmission dysregulation in DMN hubs may underlie the attentional lapses and cognitive dyscontrol characteristic of ADHD. Such neurochemical evidence aligns with network-based findings showing altered intrinsic functional connectivity correlated with impaired self-regulation in children and adolescents with ADHD [2]. [b]Together, these studies provide compelling support for a neurocircuitry model in which neurotransmitter imbalances directly impair large-scale connectivity, thereby affecting executive functions……

Taken together, this growing body of evidence converges on a multi-level model of ADHD and related conditions:

Neurochemical dysregulation (e.g., glutamate imbalance) affects fundamental brain networks.

Structural and functional abnormalities (e.g., DMN connectivity, hemispheric asymmetry, gray matter volume) shape clinical heterogeneity.

Genetic and molecular mechanisms (e.g., oxytocin–vasopressin pathways, BDNF-FKBP5 interactions) define susceptibility and resilience.

Psychosocial adversity and trauma act as modulators, with biological embedding through epigenetics and immune pathways.[/b]

Adorjan, K. Neurobiological and psychosocial mechanisms underlying ADHD and related disorders. Eur Arch Psychiatry Clin Neurosci (2025). https://doi.org/10.1007/s00406-025-02122-9

[url]https://link.springer.com/article/10.1007/s00406-025-02122-9#citeas[/url]

This interplay of genes, body chemistry and environmental factors is similar to many other major physical diseases like my own cancer, the cause of which is unknown. The fact that the cause of my cancer is not definitively identified doesn’t negate the wealth of research findings outlining the many factors involved in causation. [/quote]

Ok. That doesn’t make it any more believable that 25% of boys have ADHD. [/quote]

Are you referring to this “pop psychology” stat - 25% of adults think they have may have undiagnosed ADHD.

https://neurosciencenews.com/adult-adhd-psychology-27860/.

CDC data states that in 2022 11.4% of children have ever been diagnosed with ADHD. See more here. https://www.cdc.gov/adhd/data/index.html

Also, grow up and learn to do some real reading and understanding of health issues instead of just smearing people with misconstrued, misapplied stats. [/quote]

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