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Kids With Special Needs and Disabilities
Reply to "More evidence for folate malabsorption in Neurodivergent bodies"
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[quote=Anonymous][quote=Anonymous][quote=Anonymous]Dumb question, but why can’t you just give high doses of methylfolate (with a doctor’s oversight)? [/quote] Not a dumb question, at all..the main differences is between the two are that folinic acid is used earlier in "the folate cycle" and and methyfolate is used later so the body can convert folinic acid into different types of folate (like , but not limited to, methylfolate) but methylfolate cant do the same. So folinic acid is also used for dna synthesis and repair but methylfolate isnt[/quote] I believe there is also a concern with overmethylation. Targeting the reduced folate pathway required high doses because its just not efficient and doesn't pass much folate. You need to use higher doses ans high doses of methylfolate have many more potential side effects [/quote]
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