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[quote=Anonymous][quote=Anonymous][quote=Anonymous]OP here.  Thanks for all the helpful info.  My family history is incredibly fertile, and I have 14 first cousins who all had 3 kids each, and most of them are boys.  In addition most of my female relatives were very fertile naturally into their mid 40s.  I got pregnant right away with #1 and assumed I was also very fertile.  Now it's been almost 18 months trying for #2 with not a single pregnancy and I definitely am infertile now.  It's just really strange about my immune test results.  How can I find out if I'm genetically predisposed to this immune issue?  I have no history of autoimmune issues in my family and I don't have any autoimmune issues.  I feel the results are accurate based on my whole situation but just am having difficulty understanding why this is happening.  I feel like Mother Nature is telling me that I should not have a second child--[b]it's going to take multiple rounds of IVF plus immune treatments just to have a chance[/b] (and a very low chance) of becoming pregnant again.  The thought of putting myself through all that, plus possible ICSI, assisted hatching, PVD testing, etc. all seems like too much medical intervention.[/quote]

You don't know this.  You sound overwhelmed. I'm not sure what the immune treatments are on top of IVF but I wouldn't not to IVF if I wanted a child.  A lot of the medical intervention you mention - icsi, assisted hatching etc- isn't anything you have to undergo.  You almost sound like you don't want another child and you're arguing about how hard it's going to be.  Take it a day at a time. [/quote]

So, I am a new PP -- of course I don't know exactly what protocol has been recommended for you, OP, but thus far mine has not been bad. I did not have to deal with IVF so there's that. I did IUI which luckily worked. My immune and clotting protocol has been the following: prednisone, metformin, synthroid, lovenox, baby aspirin, intralipids as needed. This sounds like a lot but basically it works out to popping a lot of pills (prednisone, metformin, baby aspirin, synthroid, also vitamin D and prenatals which I'd be taking anyway), plus one shot per day (lovenox), plus intralipid infusions as needed. Thus far I have had a grand total of four intralipid treatments and I am 18 weeks along. The intralipids aren't bad at all. The nurse comes and hooks me up and I am free to move around while hooked up to the IV. I am able to work from home and type and do what I need. It takes 3 to 5 hours to infuse, which is enough time to do some serious work on the computer.

Just wanted to contribute my experience. The only difference between this and my prior successful pregnancy is the number of pills I take and the routine bloodwork taken every 2 to 3 weeks. The bloodwork is a pain but you get used to it quickly. I look forward to getting off all these meds after I deliver, but other than that it has been a normal-seeming pregnancy so far (knock on wood). You may have a different experience with a different protocol but if you were willing to do IVF anyway, I would not necessarily let the immune treatments put you off. I too was very worried about them but I have not had any serious side effects (high heartrate from the synthroid, some extra weight gain perhaps from the prednisone) and it's amazing how quickly you get used to them.

If you are ambivalent perhaps list your recommended protocol and let people weigh in.[/quote]

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