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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]I too am also baffled by all of this. Should I ask my PC to prescribe compound GLP-1 from a reputable or compound pharmacy or should I just go to one of the zillion sites online and do it that way? I don’t think I’ll be able to afford Wegovy or Zepbound bc neither is covered fully by my insurance and even with the coupon it’s expensive. [b]The compound versions are so much cheaper—so what’s the rub? Is it that you’re more likely to experience complications from compound than the pharma brand? Are these online places not reputable at all?[/b] Can anyone speak to their experience with compound from the big names-Hers, IVIM, Henrys? A year ago compound seemed taboo and now everyone seems to be buying it directly. [/quote]

My pcp says her concerns about safety are so grave that she won't prescribe to compounding pharmacies. She literally wouldn't be able to sleep if she did. [/quote]

Your PCP is an idiot. If they had any common sense, they would find one of the many reputable and vetted 501 B pharmacies and prescribe to you and her other patients from there. This medication is a lifesaver and compounding pharmacies are a time honored and amazing American tradition that bridges the gap for customized medicine that people need. Again, she’s an idiot and you need a new one. I literally can’t sleep right now knowing there is a doctor this stupid in the world treating patients who are stupid enough to believe her. [/quote]

You are an idiot.

Compounded medication is not regulated by the FDA and not tested for safety. You can get far more of the active ingredient than you should, or virtually none of it. My doctor has had patients sick enough to end up in the hospital due to mistakes made by compounding pharmacies. And compounded semaglutide contains a salt form of semaglutide that has not been researched at all -- for safety or efficacy. The FDA has received many reports of compounded semaglutide containing toxins. [/quote]

Please provide citations.[/quote]

NP: https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss

“ Dosing concerns with compounded semaglutide and tirzepatide

FDA received multiple reports of adverse events, some requiring hospitalization, that may be related to dosing errors associated with compounded injectable semaglutide products. These dosing errors resulted from patients measuring and self-administering incorrect doses of the drug, and in some cases, health care professionals miscalculating doses of the drug.

Additionally, the agency has received adverse event reports that may be related to patients prescribed compounded semaglutide or tirzepatide products in doses beyond what is in the FDA-approved drug label. This could mean using more product in a single dose, taking doses more frequently or increasing the amount more quickly (titration schedule). Some of the adverse events are serious and some patients reported seeking medical attention for their symptoms, including nausea, vomiting, diarrhea, abdominal pain and constipation.”

[/quote]

So read the directions and dose properly. It’s silly to have to pay 3x or more for a “pen” vs just drawing the compounded med into a syringe. Don’t be dumb (follow the dosing instructions and lay off the junk food) and the compounded meds work just fine.  [/quote]

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