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Diet, Nutrition & Weight Loss
Reply to "Weight loss drugs—is it just eating less calories??"
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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]No it is not just the calories. I lost 11 lbs in the first week and it didn't really impact my appetite until the third shot. It basically flushed all the inflammation out of my system immediately. The hormonal component is not well understood and so people who prefer simple answers reject it and insist CACO, which has been debunked in every inpatient weight loss study ever performed on obese patients, is the only answer.[/quote] One of the things that puzzles me about a rigid CACO take on it is that we know this isn't how it works in at least many other mammals. Talk to anyone who raises sheep, or cows, or other animals that they need to put weight on for slaughter - [b]certain breeds just put on more weight, and they are generally worth more to breed[/b]. I just don't get that. People who are very driven by the bottom-line will shell out more money because they know they will recoup it by getting more pound for, well, pound. [/quote] Please explain to me how this disproves CICO? No one is saying that ALL people have the same calorie needs or hormonal make up. Some people naturally have more muscle and put on muscle more easily. Some people naturally have higher or lower metabolisms. Some people are naturally more or less hungry than others. Some people can eat half their plate of food and feel fully satisfied while others clean the entire plate. We all know people who eat a few bite of dessert and say, "this is do rich, I am stuffed" where others, myself included, could eat the entire piece of cake and go back for more. No one disputes this, but just because I gain weight when eating 1600 cal/day and someone else can eat 3500 cal/day and not gain weight doesn't disprove CICO. Everyone will have a threshold where they will gain or lose weight. It just varies from person to person. No one left a concentration camp overweight. there was a podcast I listened to once with a guy who was naturally an ectomorph, tall and thin. he wanted to put on muscle and successfully put on something like 50 lbs of muscle, but in order for him to do so he had to lift weights and force himself to eat more and eat past where he felt full and wanted to stop eating. Why- because he needed to eat in a calorie surplus to gain weight. and this whole "inflammation" as the new catchphrase is just silly. most people lose water weight when they star eating better because carbs and salt cause you you to retain a lot more water. not because their bodies are "inflamed" inflammation is when you have an infection.[/quote] Because “CICO” is obviously way too simplistic if metabolism can vary so much that one person loses weight on 2500 calories but the other person has to go down to 1200 calories to lose the same weight. Or you start to gain weight on the same amount of calories that never caused you to gain before. Telling people “just eat 900 calories/day” is not a realistic approach; it’s functionally impossible for most people. I’m not sure how Wegovy etc work, but I know that differing metabolisms absolutely impact weight loss such that people making exactly the same efforts will have very different results. Anyone who had taken a medication like an SSRI that makes your weight almost instantly go up with no change in diet can tell you that something is going on far beyond “CICO.” [/quote]
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