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DC Public and Public Charter Schools
Reply to "Testing, testing, and more testing: Israel’s plan to reopen schools."
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[quote=Anonymous]Here is another study that might be useful for comprehension of this issue, since it seems to be challenging. https://www.rcpjournals.org/content/clinmedicine/21/1/e54 This one's from a hospital, but note these conclusions: False positive results in low-prevalence settings False positive results are proportionally more of an issue when prevalence is low. Prevalence is a measure of how common a disease is in a specified at-risk population at a specific time point or period.5 It measures the disease burden for the specified population.5 Prevalence affects the pre-test probability of a disease being present and consequently impacts on the positive predictive value (PPV; the probability that subjects with a positive test truly have the disease) and the negative predictive value (NPV; the probability that subjects with a negative test truly do not have the disease).3 As the prevalence increases, the PPV increases but the NPV decreases. Similarly, as the prevalence decreases the PPV decreases while the NPV increases.3 The adverse outcomes associated with false positive results will be proportionally greater during periods of low prevalence.3 However, the individual impact of false positive results are significant at all times. False positive results in high-prevalence settings [b]Although proportionally false positive results are less of a problem in high-prevalence settings when compared to true positive results, the overall percentage of false positive tests will not change.[/b] If testing increases as a consequence of high prevalence, the absolute number of false positive tests will also increase. A false positive result is less likely to be detected during times of high prevalence as the result will receive less scrutiny.[/quote]
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