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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]What are thoughts generally on higher risk of autism/mental/behavioral special needs in children carried by gestational surrogates, in terms of an immune response by the uterus to a foreign embryo causing issues?  Normally just the male half of the embryo is foreign to the mother, but in a gestational surrogate situation, the entire embryo is foreign (i.e. non-self), and from what I've read, it seems that that can cause a higher risk of autism/neurological and behavioral special needs. [/quote]

I think you made this up.[/quote]
+1
Can you cite your sources, PP?[/quote]

+100.  I would love to see a source on this.  This logic would would render higher incidences of autism in donor egg and embryo children as well.[/quote]

Agreed - your logic is flawed on a few levels.  First we would see something similar with women who use donor eggs and donor embryos (as PP said).  Second, the uterus is comprised of immune cells that more easily recognize genetics that are dissimilar from our own and in most people take steps to protect and allow implantation of the embryo.  The realm of transplant immunology actually shows that tissues like the cornea and the uterus the prefer genetic material that is not like our own.  But for organs like kidneys the body will only accept similar genetic material.  Since I won't ask for something I can't deliver, this article talks about such tissues as being "immune privileged".  This is also related to why women with many HLA matches with their husband have a hard time staying (or getting) pregnant.

[url]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448293/[/url][/quote]

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