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Infertility Support and Discussion
Reply to "When would you start wondering about implantation issues?"
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[quote=Anonymous][quote=Anonymous]OP here. To answer the other question, TNF is 30. What does this result mean? IFN is 15. My leukocyte antibody detection panel is negative, which I don't understand because I already had a baby. All my values for leukocyte antibody detection panel are all 1.0. Can anyone help me interpret these results? Additionally, when they added the IVIG some of the results got worse (higher). What does this all mean???? [/quote] Is could just mean that your body isn't so great at making B cells, which is what the LAD test looks for. Mine were in the 90th percentile so that probably has something to do with why I don't get sick very often. Being on either end of the spectrum is probably not a good thing when you want a "normal" immune response to pregnancy. Doing a few rounds of IVIG might take care of both the TNF (which isn't super high - I've seen some people with TNF that is 60-70) and the NKs. Once your immune system is in check you will be more receptive to an embryo implanting. The numbers can get worse because IVIG can seek out hidden infections and cause your body to fight those as well. Mine spiked initially on IVIG and then over the course of 4 doses my numbers were great, it just turned out that I needed the Neupogen too so once we added that I was able to get and stay pregnant. From the limited amount you put I would say yes your NKs are high but there is no reason to think that with a higher dose or with several doses of IVIG that those numbers might not come down. Otherwise there isn't anything about your situation that strikes me as particularly difficult or unique from an immune patient standpoint. I'm just saying the treatments could work for you if you decide to try them. I understand your husband has reservations, mine did too, but in the end you have to evaluate if the treatments (which many on here have done) are going to keep you from trying. I was scared when I started this process too. I had a lot of fear about the treatments and side effects and all of that is completely normal. Doing my first shot of Neupogen was stressful and I was one of the first to try that treatment! I kind of used this as an opportunity to learn more about myself and my immune system and then hopefully if something comes up as I get older I won't be starting from square 1 learning about it. I'm not sure if it helps or not but my great grandmother had a first born male and then no other pregnancies. She lived to be 94. Genetically I believe what I have was passed through this side of the family. I'm just saying it doesn't have to be an indication that there is something wrong with you or that there will be in the future. [/quote]
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