Reply to How much worse than IUI is IVF?

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[quote=Anonymous][quote=Anonymous][quote=Anonymous]
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OP here.  Thanks for sharing your story.  But here's what I don't understand--you said you were trying naturally for 3 years, how is it that your first IVF worked when 3 years of trying and that's like 36 eggs that you went through, didn't?  You're saying that you found a good egg with IVF, but how come you (and I) can't seem to get that "good egg" with years of trying naturally?

I've been trying for a year and a half naturally and haven't found my "good egg" yet.  Why would I think that one IVF would produce the good egg?  This is what doesn't make sense to me about IVF when you've been trying for over a year or more and cannot get pregnant on your own.[/quote]

It's not only egg quality, as others have said. As you age, the whole endocrine system changes. What IVF does is wipe the board clean and put in ideal concentrations of various hormones and other factors into your body at the right time, which affects how the egg and uterine lining goes on to mature. Plus you might need ICSI for fertilization (you didn't mention age of partner, but that also matters). I honestly don't think they understand that much about fertility right now, which is why they use these standardized protocols to wipe the board and start from scratch. If they did, they could probably isolate out different variables and give women more customized options.

anyway, I understand your skepticism... it might be coming from a deeper place than just puzzling over the how-to of this. Maybe you can talk to a counselor to get clear on your feelings before moving on. IF does give a lot of us doubts about the viability of our dreams and desires. Good luck.

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OP here.  Thank you for explaining this.  This actually makes a lot of sense to me, and makes me think I may want to try IVF despite my fears/concerns.  I was initially wondering how IVF could possibly work for me when I've already gone through 15 eggs trying on my own (with no pregnancy).  We have no male factor and I was successfully pregnant not too long ago, so I haven't been able to wrap my mind around why I cannot seem to get pregnant again.  But your explanation makes a lot of sense.  Thank you![/quote]

Glad that helped!  I was really reluctant to do IVF at first given my numbers so I totally get it.  It was never explained to me in these terms but slowly over the years of asking questions I feel like I understand why they do what they do.  There is a lot more research now about how the eggs and lining mature in sync with all the different hormones... it's a miracle, really, the system is so complex and delicate. Plus they have something now called assisted hatching -- as you age, the "shell" of the egg thickens, and so sometimes even if you have a genetically normal fertilized egg it doesn't hatch. But now they can make a little hole in it so that it will hatch as soon as it's transferred. Good luck to you!

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