Reply to Decision to transfer one or two embryos?

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[quote=Anonymous][quote=Anonymous]I did two elective single embryo transfers with my own eggs after age 40, and had two healthy singletons.  However, both my embryos were highly graded day 5 blasts that had tested genetically normal.

My RE pushed hard to get me to transfer two (his success rates were at stake, after all), but when I pushed back, he acknowledged that the risk of serious complications such as pre-eclampsia, cervical incompetence, cerebral palsy, micropremies is at least 5x higher with twins than singletons.  Although the chance of clinical pregnancy was statistically higher following a two-embryo transfer rather than an e-set, I felt strongly that my goal was not pregnancy, but delivery of a healthy baby.  I would have loved it if someone handed me full-term healthy twins, but I didn't think I could live with myself if I lost the entire pregnancy or had a child with serious health issues due to my desire for an instant family and stat.

If you can financially and emotionally handle the idea of doing an extra e-set or two to make up for the slightly lower pregnancy rate, and if your embryos are relatively good quality, I'm a strong believer in e-set.  Also, my OB said that the biggest mistake she sees older moms make is trying to have their kids in multiples, because those are the pregnancies where age-related issues like pre-eclampsia can really pose a problem.[/quote]

Amen.  I didn't have success with my own eggs, but I stuck to clinics that STRONGLY advocated eSET for DE.  I think it's the ethical stance, the one that considers the health of mother and baby rather than clinic stats.

I was willing to do multiple eSETs to avoid twins, but when my donors produced more than one embryo, I got pregnant on first transfer each time.[/quote]

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