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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]If someone wanted to lose vanity weight can they get a glp1?

I am 155 and 5’7”. I used to weight 125 when I got married 15 years ago. 3 kids and life got in the way. Now I am 42 and probably in perimenopause. I would love to lose 15+ pounds. Can I get a doctor to subscribe a glp1? Can I just go online and get it myself? [/quote]

You’re a normal weight. For your long term health at your age you need to focus on gaining strength and maintaining your mobility. Taking a GLP1 risks losing muscle and other side effects. The worst thing you can do in perimenopause is lose a lot of muscle and set yourself up to be frail when you’re elderly.[/quote]

Being frail is not a risk if you're not losing too much weight. None of the people I know on GLP1s look frail and they all exercise more than ever. It's a lot easier to gain strength and be mobile when you are at a good weight. I find running a lot easier now that my BMI is lower. Nobody looking at me would see me as "frail" with a 22 BMI, which is op's goal if she wants to lose 15.[/quote]

OP is not currently overweight. Her current weight is not an obstacle to being active or exercising. [b]GLP1s have the well known side effect of muscle loss.[/b] Sadly, it gets harder and harder to gain muscle in peri and menopause. Lost muscle now increases your risk of losing mobility, breaking bones, and frailty in old age. There’s no health and longevity upside to losing weight if you’re already of normal weight and health in middle age, and well documented risks.[/quote]
Stop spreading this misinformation.  GLP1 don't have the "well known side effect of muscle loss."  ANY weight loss will result in muscle loss, whether on a GLP1 or not.  The GLP1 isn't especially relevant for this.  If you lose weight, it will always be some ratio of muscle loss to fat loss.  Doing heavy lifting while losing the weight shifts the ratio so you lose more fat and less muscle.  Not doing the strength training means you'll lose more muscle.

If OP goes on a GLP but also does weightlifting, then the muscle loss won't be a concern.  If OP does not go on a GLP and loses weight through dieting without doing the lifting, then OP will lose a lot of muscle mass.   The key here is the weightlifting, not the GLP. [/quote]

“ CR studies show a trade-off in weight loss composition. While around 60% of weight loss comes from fat mass, approximately 30% comes from lean mass. This proportion fluctuates based on factors such as sex, age and the severity of calorie restriction (more severe CR leads to greater muscle loss), and dietary composition.”

You can mitigate the loss of muscle by losing weight slowly and lifting weights, but most people don’t. The worst case scenario is to lose weight, muscle and fat, go off the medicine, then regain the weight, except regaining it as all fat. Certainly, some people can go off a GLP1 and keep the weight off, but most don’t.

People’s experiences vary, but you shouldn’t go into taking a serious medicine for vanity assuming that you will have the best case scenario: minimal side effects, weight training and optimizing diet to avoid muscle loss, and maintaining the weight loss after going off the meds.

I also can’t imaging risking my marriage to lose vanity weight. Lying to your spouse about something this significant is an enormous breach of trust.[/quote]

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