Reply to Husband has Sickle Cell gene and didn't tell me

Forum Index » Expectant and Postpartum Moms

Reply to "Husband has Sickle Cell gene and didn't tell me"

Subject:

Emoticons





More smilies

Text Color: Font: Close Marks

[quote=Anonymous]You’re not wrong to be concerned. It’s rare, but there are folks with sickle cell trait (rather than sickle cell disease) who do experience symptoms.

“Established co-morbidities associated with sickle cell trait include exertional rhabdomyolysis, pulmonary emboli, splenic infarction with high altitude, and renal diseaseii and renal medullary cancer of the kidney.ii“

“Scientific literature has historically suggested that SCT is a benign condition, but it is increasingly clear that this is not the case. SCT has been linked to hematuria, chronic kidney disease, sudden death due to exertion, glaucoma, rhabdomyolysis, splenic infarction and other clinical phenomena. A study of American football players found that patients with SCT had a 37-fold higher risk of exertional death than their counterparts without the trait. Another study found that there is a 54% higher chance of developing rhabdomyolysis during physical exertion in the presence of SCT. In recognition of our increased knowledge in this therapy area, screening policies such as that of the National Collegiate Athletic Association in the US are being used to identify people at risk of exertional death because of SCT.”

“Sickle cell trait is exclusively associated with rare but often fatal renal medullary cancer. Current cumulative evidence is convincing for associations with hematuria, renal papillary necrosis, hyposthenuria, splenic infarction, exertional rhabdomyolysis, and exercise-related sudden death. Sickle cell trait is probably associated with complicated hyphema, venous thromboembolic events, fetal loss, neonatal deaths, and preeclampsia, and possibly associated with acute chest syndrome, asymptomatic bacteriuria, and anemia in pregnancy.”[/quote]

Options

	Disable HTML in this message
	Disable BB Code in this message
	Disable smilies in this message

Review message

Search Recent Topics Hottest Topics