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Perimenopause, Menopause, and Beyond
Reply to "Topical estradiol cream felt systemically "
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[quote=Anonymous]Vaginal estrogen is not systemic, but I believe I've read that upon initial use systemic levels can rise in some women very slightly, then they go back to baseline. That may be what you are experiencing. But vaginal estrogen is such a low dose, it's not going to have systemic effects. I find I sleep better on the nights I use it because I'm less likely to get those middle of the night urges to pee. But even systemic estrogen is not going to help you sleep, it's the progesterone that does that. I would say the mood and hair loss is just a coincidence. [/quote]
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