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[quote=Anonymous]I tried Zoloft and other SSRI's, and both times, I gained at least 40 pounds.  I got the weight off the first time, and am still struggling with the second.  One theory is that for some people, SSRI's raise blood sugar by just a tiny bit... not enough to create diabetes, but enough that the body pulls that blood sugar out of the blood and stores it as fat in order to keep stabile blood sugar levels.  If that is happening all the time, weight goes up month after month at an alarming rate.  I would try anything else you can before beginning these drugs.  If you do try them, keep a close eye on your diet, and if your weight goes up in the first or second month, quit them.  I believe that the research into SSRI's only lasted a few months, and so when the reference literature says the drugs cause only a moderate weight gain of 5 to 10 pounds, it is because the test subjects were not followed and tracked long enough to capture the significant weight gain of over 30 pounds that many experience.    [/quote]

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