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[quote=Anonymous]17:59 - Get over yourself.

We evolve as people.  Our bodies adapt to our surroundings.    Look at the Eskimos - http://anthro.palomar.edu/adapt/adapt_2.htm

In terms of Tay Sachs . . .

How common is Tay-Sachs disease?

Tay-Sachs disease is very rare in the general population. The genetic mutations that cause this disease are more common in people of Ashkenazi (eastern and central European) Jewish heritage than in those with other backgrounds. The mutations responsible for this disease are also more common in certain French-Canadian communities of Quebec, the Old Order Amish community in Pennsylvania, and the Cajun population of Louisiana.

So it's NOT specific to Jews.

And - How do people inherit Tay-Sachs disease?

This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

So BOTH parents must have the gene. Again, area is important.  A Jewish community will be insular.

And we have this:

Italians like Macri aren't the only Mediterranean descendants affected by blood disorders such as beta thalassemia. People of Greek, North African, Sephardic Jewish, and Arab descent have a higher incidence as well. The disease causes severe anemia and appears in infants in their first four to six months of life.

And this:

"Genes are very mobile," Glader explains. "What you see reflects history: the Romans travelled." The sickle gene arrived in Mediterranean countries from central West Africa through the trade routes across the Sahara. This may account for the occasional case of sickle cell disease among European Americans who trace their ancestry to southern Italy, Sicily, Turkey or Cyprus. Not all disease genes are identical by descent. The same mutation can occur more than once in the same or different populations.[/quote]

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