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[quote=Anonymous][quote=Anonymous]No one knows much about an emergency use approved vaccine that can alter your DNA-anyone who says otherwise is full of it. Agreed that in a pandemic backs are against the wall, but the immediate risk of Covid is now over.

Signed, a physician[/quote]

No, COVID-19 vaccines do not alter human DNA. The vaccines, particularly those using messenger RNA (mRNA) technology, work by instructing cells to produce a protein that triggers an immune response against COVID-19. They do not interact with or integrate into the DNA within the nucleus of human cells.

The mRNA in COVID-19 vaccines is a single-stranded copy of a small part of DNA that is used to send instructions to other parts of the cell. It is broken down quickly by the body and never enters the nucleus, where human DNA is stored. Therefore, it cannot affect or combine with our DNA to change our genetic code[1].

Experts, including those at the U.S. Food and Drug Administration (FDA), have stated that concerns about DNA fragments from mRNA vaccines entering the human genome and causing harm are unfounded. The mRNA vaccines are designed to work outside of the cell nucleus and have not been observed to interact with the nucleus[4].

Additionally, a Swedish study that was misinterpreted by some social media users did not demonstrate that the Pfizer COVID-19 vaccine alters the human genome. The study found that mRNA from the vaccine could be converted to DNA in lab-altered liver cell lines under experimental conditions, but this did not assess whether the vaccine alters the human genome or what the effects of that would be. Experts have stated that additional research is needed because the findings in the lab setting cannot be used to make inferences about what happens in the human body[7].

Dr. Paul Offit, an expert in the field, has explained that the way mRNA vaccines are made does result in small amounts of DNA in the final product, but these are trace quantities that are harmless. The residual DNA would have to overcome multiple barriers to enter human cell nuclei and integrate into the nuclear DNA, which is highly unlikely[6].

Furthermore, the concerns about DNA fragments from mRNA vaccines causing sustained autoimmune attacks or future cancer are theoretical and not supported by evidence. The mRNA vaccines do not contain replicating vectors, meaning they do not have the sequences necessary to make copies of themselves even if they did get into a human cell. The likelihood of contaminating DNA present in the vaccine impacting the human genome is astronomically low[3].

In summary, the consensus among experts and health authorities is that COVID-19 mRNA vaccines do not alter human DNA[1][4][6][7].
Signed,

Chatbot, with better references than above Physician,

Citations:
[1] https://www.health.gov.au/our-work/covid-19-vaccines/is-it-true/is-it-true-can-covid-19-vaccines-alter-my-dna
[2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876036/
[3] https://www.orfonline.org/expert-speak/can-the-covid-vaccine-change-a-persons-dna
[4] https://www.nebraskamed.com/COVID/you-asked-we-answered-can-mrna-vaccines-alter-human-dna
[5] https://www.scstatehouse.gov/CommitteeInfo/SenateMedicalAffairsCommittee/PandemicPreparedness/Phillip-Buckhaults-SC-Senate-09122023-final.pdf
[6] https://www.scientificamerican.com/article/no-covid-mrna-vaccines-wont-damage-your-dna1/
[7] https://apnews.com/article/fact-check-covid-vaccine-sweden-study-986569377766
[8] https://www.chop.edu/video/do-dna-fragments-covid-19-mrna-vaccines-cause-harm[/quote]

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