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[quote=Anonymous]At Amicus Therapeutics, the new tax law solved a geographic dilemma. The Cranbury, N.J., company is developing an experimental drug to treat Pompe disease, a rare inherited disorder that causes muscle weakness and can be fatal.

After early results for a new drug proved promising, Amicus decided a year ago it would increase production for further clinical testing and potential commercial sales, Chief Executive John Crowley said in an interview.

Amicus, which had been using Chinese contract manufacturer WuXi Biologics to supply the drug, decided in August to build its own facility. The U.S. was at a disadvantage to Europe, due to its 35% statutory federal income-tax rate for companies. [b]Ireland’s corporate tax rate, by contrast, is 12.5%.[/b]

Those financial considerations threatened to overshadow other advantages that a U.S. plant would offer, including the ease with which company officials could visit it, and the availability of talented workers in some regions.

“Our strong assumption was that it would be very challenging to establish a new bio-manufacturing facility in the U.S,” Mr. Crowley said.

As the tax legislation advanced in Congress last fall, however, building in the U.S. began to look more attractive. On Dec. 21, a day after Congress passed the final measure, which lowered the statutory corporate rate to 21%, Mr. Crowley recommended to his board the company focus on finding a U.S. site. The company has narrowed its choice to three East Coast cities Mr. Crowley declined to identify, and expects to decide in the next month or two. [b]It expects the plant to cost $150 million to $200 million, and to employ at least 200 people at an average pay of $100,000 a year.[/b]

“With the changes in the tax law, it now makes the U.S. competitive with these geographies we’re looking at,” he said.

https://www.msn.com/en-us/money/companies/the-tax-law-just-one-month-old-is-roaring-through-us-companies/ar-AAvauNM?li=BBnb7Kz[/quote]

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