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Infertility Support and Discussion
Reply to "No blasts on day 5/6"
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[quote=Anonymous][quote=Anonymous][quote=Anonymous]I m 42 and started ivf last year when i just turned 41. Cycle #1 14 retrieved 12 fertilized with icsi 4 blastocysts Pgs - all abnormal Cycle #2 15 retrieved, 11 fertilized with icsi 0 blastocyst Cycle #3 Started taking coq10, dhea ( thermalogix) acupuncture (3or 4 times a month) 16 retrieved, 14 fertilized with icsi 5 blastocyst Pgs - all abnormal Cycle #4 ( took a break for couple of months) At this point i lost my faith in ivf and just did it for heck of it. So i could tell my self in the future I did my best and try as hard as i can. Since insurance covered I thought what the heck. 18 eggs retrieved, 7 fertilized with icsi Fresh transfer on day 5 1 early blast grade 1ab 1 doc said it looks like its about to blast 1 i ve no idea ;) just wanted to transfer 3 due to my age.. I m pregnant with singleton. First beta 14dpt. 1760 Second beta. 16dpt 4000 Third beta 20dpt 17000 Ultrasound normal heart beat.. I agree with the posts about pgs testing. They are not 100% correct. Studies shown mosaics embryos may self correct themselves in uterus. Please do some research and you will find out. Also as far as i know ( i might be wrong) in ivf, most chromosomally abnormal pregnacies end up miscarriage. I remember reading somewhere also an embryologyst friend confirmed as well. But as i said i might be wrong.. Some embryos do better in moms belly rather than dish. I suggest try a fresh transfer. Transfer 1 or 2 and if there anything leftover for blastocyst you can freeze it. I wish you the best of luck.. it doesn't have to try to try something different ())[/quote] PGS testing doesn't detect mosaicism at all. Yes, some studies say that there have been some cases (not massive studies that are methodologically controlled, but individual case reports) of aneuploid embryos self correcting. It doesn't mean that every PGS abnormal embryo can self correct, so it's still a big risk. Also, on petri dish vs. "mom's belly" - transfer on day 5 places the embryo in the uterus. In a spontaneous non-ART pregnancy, embryos make it to the uterus sometime between day 7 and 9, [b]so day 5 transfer places the embryo where it wouldn't yet be otherwise. [/b][/quote] Would that contribute to early demise of many PGS normal embryos? They treat all FETs as day 5 transfers.[/quote]
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