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Infertility Support and Discussion
Reply to "No blasts on day 5/6"
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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]I've also had a very low blast rate but am a high responder. Even at 150 Gonal F and 75 Menopur, I still just retrieved 14 eggs, yet I typically make 1 blast or even none. Like PP, I also tried two fresh transfers of 5 Day 3 embryos each. I don't think those were good quality cycles for a few different reasons, and they weren't on immune treatment, so who's to say whether that approach would really work any better for me. My current RE doesn't think the Day 3 approach is good for me because I always have too many to choose from at Day 3 and there is no good way to discriminate between them. She said the most recent normal embryo I had would not have been among the ones selected for a Day 3 transfer. So I feel a little bit stuck. I've already had 3 miscarriages due to chromosomal abnormalities, and two were late in the 1st trimester, so I am not eager to repeat that without PGS testing. I've had two normals, tried transferring one so far and it did not take. I'm going to try again next year with the one in the freezer on immune protocol. [/quote] Thanks for your post. What will immune protocol include? And how did you conclude you needed one?[/quote] Immune protocol for me will involve a steroid like prednisone, intralipids, and maybe Neupogen. I'm not seeing Dr. Braverman, but he believes high dose fish oil is just as good as intralipids. It used to be that I could get pregnant somewhat easily with bad embryos (hence the three miscarriages due to chromosomal abnormalities), plus one live birth in the middle of all of that. Right after the 3rd miscarriage, it seemed like a switch flipped and I couldn't get pregnant even though it seemed like implantation was in process (implantation bleeding and cramping). After 6 IUIs, a failed FET with a normal embryo, and Day 3 transfers of 10 beautiful looking embryos, I just felt like I should have had SOME pregnancy, even a bad one, given my history. I had heard that immune issues can be triggered by pregnancy, especially a male, and that third miscarriage was a male fetus. I don't know if that's for sure what happened or not, but I just felt something wasn't right. I already knew I had Hashimoto's, which is an autoimmune disease, so I went to have testing done with Dr. Abbasi at CFA. I do have natural killer cell activity and cytokines outside the normal range. [/quote] Thank you. I hope things work out for you on next try.[/quote]
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