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[quote=Anonymous][quote=Anonymous]There isn't a way for a follicle to shrink, as such. But it is a squishy three-dimensional object that the ultrasound is only seeing a two-dimensional slice of. So it is not unusual for the measurements to fluctuate up and down.

I can understand why you want to know whether and, if so, how much a follicle grows between the last ultrasound, the end of stimulation, and between the trigger and retrieval. I hope it isn't too frustrating to say that it doesn't really matter. This is all about the odds, and from a statistical process control perspective, what matters is (1) the last measurement, (2) the process adjustment, and (3) the ultimate success rate. In other words, the protocol is optimized based on what was seen at everyone's last ultrasounds.

There is some evidence that adding follicle measurements to total estrogen levels doesn't significantly improve the quality of the decisions about how much to stimulate and when to trigger. Generally, they will be looking for an appropriate rate of increase and a level that is consistent with the number and size of follicles seen.[/quote]

Thanks so much for in depth explanation![/quote]

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