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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][url]https://www.npr.org/sections/coronavirus-live-updates/2020/04/21/840341224/nih-panel-recommends-against-drug-combination-trump-has-promoted-for-covid-19[/url]

[quote]A panel of experts convened by the National Institute of Allergy and Infectious Diseases recommends against doctors using a combination of hydroxychloroquine and azithromycin for the treatment of COVID-19 patients because of potential toxicities.

"The combination of hydroxychloroquine and azithromycin was associated with QTc prolongation in patients with COVID-19," the panel said.

QTc prolongation increases the risk of sudden cardiac death.

The recommendation against their combined use would seem to fly in the face of comments made by President Trump suggesting the combination might be helpful. On March 21, for example, the president described them in a tweet as having a "real chance to be one of the biggest game changers in the history of medicine."[/quote][/quote]

[/quote]

[quote]The data for QTc prolongation is originally based on data from Clarithromycin, a drug in the same class.  Azithromycin has not demonstrated the same properties, the case reports in the literature are under a handful.  Caution is recommended in certain classes of patients, patients with electrolyte disturbances, underlying cardiac disease, existing QT prolongation disorders, patients taking multiple drugs which prolong QT interval, and frail elderly.  Z-packs are given out by the millions to patients every day, as outpatients.  Many of those same patients are already on Hydroxychloroquine for RA and lupus. Current guidelines recommend screening and monitoring to manage possible side effects and evaluate risk/benefit.  Trump is not your doctor, and your doctor is very capable of making these assessments.[/quote]

Wow, you're smarter than a panel of NIH convened experts?  Amazing! We are blessed to have you here on DCUM.  [/quote]

[b]This issue should be looked at critically from both sides rather than politicized in either direction. [/b] These drugs are not new, neither is the warning of the QTc interaction.

Is that all you’ve got?[/quote]

Yes, Trump, a politician not a doctor, should have never uttered the word hydroxychloroquine out of his puckered up little face sphincter.

He is incompetent and should be removed before more people DIE.

[/quote]

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