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Reply to "How, exactly, does Ozempic work? "
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[quote=Anonymous][quote=Anonymous][b]So no one can answer OP’s actual question? [/b] I have one friend on one of these drugs. She was diabetic and could not lose weight. It probably saved her life. She is at a relatively average weight for her height now and feels much better. Another friend has been yo-yo dieting for years. Mostly to lose that last ten pounds. Saw her recently and thought she must be ill till I realized she’s probably on one of these drugs. She looks bad but she seemed quite happy.[/quote] It is a glucagon-like peptide-1 (GLP-1) agonist. It binds to GLP-1 receptors on pancreatic islet cells and some brain neurons. This triggers release of insulin, inhibition of glucagon secretion, and inhibition of gastric emptying. Did you want more? Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1 https://pubmed.ncbi.nlm.nih.gov/29617641/ Glucagon-Like Peptide-1 Receptor Agonists https://www.ncbi.nlm.nih.gov/books/NBK551568/ What is a GLP-1 agonist, and how does it work? (Ohio State Medical Center) [youtube]https://www.youtube.com/watch?v=KeqMSzFbSos[/youtube] GLP-1 Agonists: What They Are, How They Work & Side Effects (Cleveland Clinic) https://my.clevelandclinic.org/health/treatments/13901-glp-1-agonists [/quote]
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