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Relationship Discussion (non-explicit)
Reply to "Test results came back positive"
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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]OP here- already talked with my doctor. Talking to another doctor later this week. Only real probability was a recent partner. I don't know why the type of std matters.[/quote] It matters because HPV can be in your system for years and then reactivate. [/quote] Not really. Usually your body completely clears an hpv infection or you will continue to test positive for it. By “laying dormant,” it means the hpv infection isn’t causing any precancerous cells, not that it’s undetectable. If someone tests negative for hpv and then tests positive, it almost always means they have a new infection. [/quote] That is completely wrong.[/quote] [quote]No, it’s not. As long as the hpv is in your system, even if you have no symptoms of infection and no cellular changes, you will test positive for it. For most people, hpv clears itself COMPLETELY in about two years, but in some people it can last decades. If you tested negative and then test positive a few years later, you have a new infection. FACTS.[/quote] [quote]No. It does not mean it is a new infection. It can recur years later: the same one. [/quote] [quote]Not 10 years later though. [/quote] Yes, 10 years later. Lag period is not the same as latency. Alos, Trichomoniasis is NOT like a viral infection such as HPV, which can and does sometimes establish latency. [quote]The incorporation of HPV DNA testing into cervical screening programs has shown that many HPV-positive women are cytologically normal, with HPV-positivity fluctuating throughout life. Such results suggest that papillomaviruses may persist in a latent state after disease clearance, with sporadic recurrence. ... Viral latency is well recognised as a phase in the life cycle of some viruses, where after initial infection, the production of new virus particles ceases, without the eradication of the virus from the body. In these situations, latency is linked to the possibility of future reactivation and renewed virus particle production as the host immune response changes over time. One of the best characterised example of this is Shingles, which is a re-emergence of a productive Varicella Zoster infection of the skin, which can occur many years after the resolution of chicken pox [1,2]. [b]Our current concepts of papillomavirus latency and reactivation have to a large extent been derived from studies carried out in animal infection models, and appear to fit this definition of ‘viral latency’ [/b] ... It is clear however, that in some situations, the genetic background of the host affects the course of disease following HPV infection, with defects in the EVER genes [34] or CD28 (amongst others [14,35]) predisposing to the proliferation of cutaneous lesions in EV and Tree man syndrome patients, or CXCR4 mutation which contributes to HPV susceptibility in WHIMS individuals [36]. ... with different HPV types having inherently different persistence probabilities that are linked to the genetics and immune status of the host. ... In addition, several studies have shown that HPV positivity can fluctuate over a woman’s lifetime and that the re-occurrence, often after repeated negative HPV tests, shows no apparent correlation with the acquisition of a new sex partner, but can occur in women who are not sexually active at the time of HPV testing, or who are in a stable partner relationship [46]. Given our knowledge of chronic viral infections, and our understanding of the basal cell reservoir where HPV genomes can persist, the simplest explanation is that [b]HPV infections can persist subclinically, and that the levels of HPV DNA at the cervix can sometimes rise above the clinical detection threshold, and can in some individuals, oscillate above and below this threshold throughout life. [/b] [/quote] https://www.sciencedirect.com/science/article/pii/S2666679023000150[/quote]
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