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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]Hi, OP. DW and I were in a similar situation a few years ago. She did a cycle at Shady Grove and we ended up with two embryos that made it to blast. We transferred one and froze the other. The first transfer took, but we lost the pregnancy due to chromosomal abnormalities. At that point we decided to test the remaining embryo, which required thawing it, doing a biopsy, then refreezing while we waited for results. Although the embryo was normal, we believe that the freeze/thaw/freeze/thaw, as well as the biopsy, really interfered with successful implantation. It was only 80% thawed and it didn't stick. Makes me really wish we'd never tested it, and that we had just transferred.

For what it's worth, my DW recently became a patient of Dr. Braverman. Among other things, he told us that when she does her next cycle, we should do a freeze all and NOT test them. He also told us that while PGS does identify chromosomal abnormalities, there are also instances where PGS tested "abnormal" embryos are not, in fact, abnormal (based on a small study he did with his own patients). He also said that the biopsy can do more harm than good in some cases. Now, if you're a person with like 20 embryos, then I could see the sense in testing to at least narrow down what to transfer. However, if you only have a few - which will likely be the case for us (if we're lucky) - it doesn't necessarily make sense to test them. [/quote]

OP here, thanks for your post.  This is my biggest concern - that our embryos are normal but that we'd lose some due to the stress of biopsy, and then not have any at all to transfer!  I guess it's weighing the risk of possible miscarriage due to chromosomal issues, or risk of not having any remaining frozen embryos to transfer.  That's a tough one...[/quote]

PP here. Yes, it's really tough. My DW had to TFMR with the chromosomally abnormal pregnancy, and that was the worst thing that has ever happened to us. Darkest point in our lives, no doubt. I wish I had better advice for you! Good luck to you.[/quote]

Thank you for posting your experience. I am getting ready for FET, and I was debating whether I should go for PGS or not. [/quote]

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