Reply to help! the lab messed up our PGD results!

Forum Index » Infertility Support and Discussion

Reply to "help! the lab messed up our PGD results!"

Subject:

Emoticons





More smilies

Text Color: Font: Close Marks

[quote=Anonymous][quote=Anonymous]Not 15:03, but PGD and CCS are two different ways to test an embryo and your clinic shouldn't use the terms interchangeably.  PGD is testing 3-day embryos and has not been shown to improve pregnancy rates in couples who do not have a specific, identified genetic issue.  CCS (sometimes called CGH) tests 5-day embryos (and the sample is actually taken from the cells that become the placenta...pretty cool) and the pregnancy rates are significantly higher and miscarriage rates are significantly lower.[/quote]

This isn't accurate.  PGD is an acronym for pre-implantation genetic diagnosis.  The original technique for pre-implantation genetic diagnosis involved day 3 biopsy and only tested a handful of chromosomes.  The PGD technology has now advanced so that the biopsies are done on troph cells on day 5 and all chromosomes can be tested.  The term CCS is an acronym for comprehensive chromosomal screening, which is a descriptive term coined by CCRM and later adopted by a few other clinics.  There are many different ways to perform CCS, and at different times in the past four years, CCRM has used CGH, microarray, and real time PCR.  All of these technologies are diagnostic in that they look at genetic matter amplified from actual cells rather than looking at soft markers, but because the tests are still experimental and imperfect, and because the one or two troph cells biopsied may in a small percentage of cases differ from the majority of embryonic cells (mosaicism), clinics often refer to the technology as a screening test.[/quote]

Options

	Disable HTML in this message
	Disable BB Code in this message
	Disable smilies in this message

Review message

Search Recent Topics Hottest Topics