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Infertility Support and Discussion
Reply to "Progesterone suppositories - extreme TMI!!!"
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[quote=Anonymous]I'm going to vote for the PIOs. The shots are not fun, but also not too bad, you really get used to it. Most nights it's just a little poke, sometimes you bleed and need a bandaid. I had at least a little dread each night but now that I'm weaning and using suppositories, I miss the fact that there was no mess. It's not clear that PIO is better than the suppositories, but it seems it gives you higher blood levels (the suppositories deliver progesterone directly so it can't always be measured in the bloodstream). If not the PIOs, then I second the use of the PreSeed applicator to get it up there. I find that if I get it up there really far, I have less leaking.[/quote]
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