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Diet, Nutrition & Weight Loss
Reply to "I ate more on zepbound and lost 20 lbs"
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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]I am eating more and losing as well. Or rather, [quote]I’ve increased my BMR[/quote] and can maintain at a higher calorie intake, and lose more easily when I cut calories. People posting here have very very simplistic ideas of how metabolism and weight loss work. [b]I believe you OP[/b].[/quote] so you're saying Zepbound changes metabolism for you and op?[/quote] I’m saying it did. And yes, there are studies out there about this. It treats insulin resistance. [/quote] Google says... [b][i]Although basal metabolic rate (BMR) is involved in glucose homeostasis, existing evidence regarding its association with insulin resistance (IR) remains inconsistent across populations. [/i][/b] Jul 1, 2025 [b]BMC Endocrine Disorders [/b]https://bmcendocrdisord.biomedcentral.com › articles [b]Association of predicted basal metabolic rate and insulin ...[/b][url]https://bmcendocrdisord.biomedcentral.com/articles/10.1186/s12902-025-01976-3#:~:text=Although%20basal%20metabolic%20rate%20(BMR,IR)%20remains%20inconsistent%20across%20populations.[/url][/quote] It also says: Zepbound (tirzepatide) increases insulin sensitivity by stimulating the pancreas to release more insulin in response to glucose and by improving how the body uses insulin. As a dual GLP-1/GIP receptor agonist, it mimics the actions of two natural hormones, which lowers blood sugar levels and improves how the body handles insulin. Increased insulin sensitivity promotes weight loss because it allows the body to use glucose more effectively for energy instead of storing it as fat. With higher sensitivity, the body requires less insulin, which reduces the signals for fat storage and can lead to a decrease in overall body fat and weight. In contrast, insulin resistance encourages the body to store fat, making weight loss more difficult. —why are you so pressed about this PP? [/quote]
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