Reply to People who exercise a lot - do you have unusually high HDL?

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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]Until this post, I had not heard that physicians were concerned with high HDL anymore.  My labs don’t even show a preferred upper limit.[/quote]

They aren’t concerned.  Only LDL high numbers are a problem.[/quote]

This is not true. In the past decade, there have been a number of studies showing a bell-curve effect regarding very high HDL (over 100), and an increase in all cause mortality risk (heart disease, cancer, stroke, etc). Too low HDL isn't good. Too high, is also not good. [/quote]

Agreed, but I would also say the answer is never so black and white. The answer is, its complicated and there are so many confounding variables.

In the end, you do the research you can and optimize the best you can - within reason. Or, do nothing and trust the guidelines. Otherwise, you will end up down some weird Peter Attia fueled Lipidology rabbit hole. I somehow got the petter attia subreddit on my feed on reddit and those dorks are something else. 26 year old men trying to optimize their already more than satisfactory LDL numbers with statins, instead of doing reckless shit they won't have the time to do or the sense not to do later in life. [/quote]

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