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[quote=Anonymous][quote=Anonymous]I’ve posted before so I don’t want to repeat because someone will think I’m a drug rep but here goes. I was included in a study conducted by NIH for semaglutide for almost 2 years. Started Nov. 2018. Starting weight was either just over 300lbs or just below, can’t remember and I don’t want someone to dig up one of my old threads and call me a liar. But it was somewhere around 300lbs. Ended the study Nov. 2020 @ 182lbs. Lowest weight was June 2020 167lbs. I wanted to be 170 by my 50th Birthday. I purposely gained weight back because I thought I looked gaunt at 167. Just looked too thin in the face. I thought I looked like someone who had lost weight due to illness.

By February 2021, I was back up to about 225lbs. But honestly, I wasn’t trying to maintain, COVID isolation was getting me down, my mom was severely ill with Covid-19, I had started a second job, stopped going to the gym and just generally DGAF. But by March, I was ready to get back at it.

My doc from the study then prescribed Rybelsus 14mg (the diabetic flavor of the medication). Current weight is 192lbs. Goal weight is between 177-180lbs.

While I was in the study, they basically told me that this would be a lifelong drug. Or until I stopped caring about my weight.

Side affects: Some nausea, feeling cold all the time, some diarrhea in the beginning, and when you are full, you are full, your belly won’t take another bite or you will be miserable until you poop it out.

The dosing was gradual. Started with .25mg to top dose of 2.4mg.

This medication is not at like phen-fen or any type of stimulant.

It is expensive, but the manufacturer has a coupon to cover the first 6 scripts or at least they did on the Rybelsus.  My doc has written me a script for the Wegovy, but it is very hard to find. I’ve been trying to get it for 6 weeks.

If anyone wants to know more from my experience from being in the study I’m more than happy to share. Also search Semaglutide in the diet forum and you will find a couple of the threads that I’ve talked about my experience.[/quote]

Thank you so much for this helpful info.  What did you do about the nausea?  What did you feel like when you went off the medication?  Did your appetite come roaring back? Are you able to live normally (like exercise, sleep, etc)?  [/quote]

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