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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]What kinds of cancers and the ages at death? I'm a cancer researcher and my husband has a crazy family history two died in their 40s from brain cancer and melanoma of the eye. Two survived colon cancer and a third survived prostate cancer. Literally every member of his family on that side had cancer. Unfortunately for my husband there is no clear pattern. His family could have something majorly wrong (tumor suppressor deletion) but I highly doubt anything would be definitively identified and if it were there wouldn't be a cure. Cancer therapy is like a sledge hammer. Kill it before it kills you. I just encourage my husband to get early and often screenings.[/quote] My family has the BRCA 2 mutation and has had tons of different cancers, including pancreatic (both types, neuroendocrine and adenocarcinoma), colon, brain, skin, ovarian, lung, and liver. I am taking the sledge hammer approach myself. It’s just strange because BRCA is most often associated with breast cancer and we have none. I was shocked when we had a positive BRCA mutation in the family. [/quote] He did 23andme and was BRCA negative...[/quote] I’d recommend the Color test or a genetic counselor because 23andme only tests for the most common types of BRCA mutations (known as the “founder” mutations). Lots of people get false positives with 23andme.. my BRCA 2 mutation is not one of the ones it tests for. Dangerous stuff. [/quote]
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