Reply to Any over 35 moms elect for CVS/Amnio after negative NIPT results?

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Reply to "Any over 35 moms elect for CVS/Amnio after negative NIPT results?"

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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]Why would you do the screening if you don’t the results? 
The point is screen and then diagnose if screening is abnormal. [/quote]

Yes, that’s the whole point. Talk to someone about your anxiety. No guarantees in life OP. They can pick up stuff at ultrasounds they can’t pick up through amino. Healthy fetuses can suffer oxygen deprivation at birth and end up with brain damage or cerebral palsy. If your NIPT was good, just relax. You’re not that old, and the risks are not that much higher at 37 than say, 30. If you were 47, maybe, but you’re not. [/quote]

OP here, this isn’t about anxiety, it’s about the benefit of a diagnostic test versus a screening. I was looking for other moms who have considered this issue and wanted to get their thoughts. Obviously there are no guarantees with anything involving pregnancy and childbirth, or for that matter child rearing, but as a PP mentioned, there is an appeal to the level of comfort a diagnostic test provides as opposed to a screening. It sounds like several other PPs had similar concerns, so I’m hardly alone in thinking about these issues. [/quote]

Seems like anxiety to me. I’d be surprised if insurance would cover an amino without a reason. That’s why they do the screenings first. [/quote]

Most insurance companies have no problem covering amnio or cvs for women over 35. It's a normal test when you are AMA. As long as your OB orders it and states you are AMA it should be no issue.Because if there is in fact something that very wrong it saves them money in the long run.

Honestly I will never understand the reactions people give when moms want diagnostic testing. Why are you all so against it? The risk to the fetus is literally almost nothing with experienced MFMs. Get over it. [/quote]

Thank you, I’m not sure why people are telling me to get treatment for my supposed anxiety over this. As I said, we would absolutely terminate in certain circumstances, so that is part of why I want definite information. My insurance company said they will cover either CVS or amnio based on my age, so that’s a non-issue. I’d be willing to pay OOP if necessary anyway. [/quote]

I'm the pp and Honestly anxiety about your child being healthy is normal. I'm surprised how many people don't seem to be concerned at all when they are older and having babies. I mean good for them but I'm all about information. It's available so I want it. It's pretty cut and dry to me. When are you due?[/quote]

Thank you! Yes, like you, I prefer more information whenever possible. I’m due 9/25 but I’m sure I’ll be induced again since I have GD with this pregnancy as well. [/quote]

I'd be a lot more concerned and focusing my attention on the real risks and problems associated with GD than the unknown (and often indefinite) information an amnio could possibly provide beyond confirmation of the NIPT/ultrasound negative screens that, although small, presents a risk to the baby. You're apparently worried about the 1:10,000 (or whatever...) chance the screeners are "wrong," but not the 1:1,000 chance that this diagnostic test could cause an adverse outcome for the pregnancy?

Sorry if that sounds snarky, but having just been through the entire amnio/genetics process starting with non-negative NIPT results, I wouldn't jump into it after every zero-risk test and screener has told me there's no indication for it, and especially not being *that* AMA. If you proceed with just FISH/karyotyping, you will still only see chromosome-level abnormalities (mostly the same info as the 1st tri screeners are looking for). The microarray provides much, much more information, yes, but a lot of it is knowledge that we don't have full understanding of - and the potential to create a lot more worry and anxiety for someone who appears to be prone to that already. Your genetic counselor will likely discuss with you that a number of the deletions/duplications they can find in the results are not 'diagnostic' in the sense that we can tell these patterns have been found in individuals with say, schizophrenia or ADHD, but is it causative? We don't microarray reasonably healthy individuals or even every person with a particular condition, so there's no data to say that 50%, 70%, 95% likelihood of this genetic error resulting in your child developing this condition. What kind of decisions and worry are you faced with if you recieve THAT information? We microarrayed because our screening results were indicative that it could be a dup/del issue, but waiting on those results and considering what information we might find was really concerning - and I'm not generally a worrier.

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