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[quote=Anonymous]As long as your husband has a very thorough genetic screening (I recommend going through Ambry genetics if possible, it's what CF clinics use for genetic testing), go for it.  Both biological parents have to be carriers in order for a baby to have CF. My husband has CF so all our children will be carriers.  There's no need or possibility of doing PGD unless your husband is a carrier.  I believe CF is carried by about 1/25 Caucasian people, so it's not unusual to be a carrier.  We actually found out after my daughter was born, that I was a carrier for 2 other diseases that weren't included in our initial IVF genetic testing, so my daughter has possibly inherited more rare disease genes from me than from her father.

That being said, there are a couple thing I  would warn about having a child that's a CF gene carrier.  A) sometimes men who are even just carriers for CF are born without a vas deferens.  It's why we had to do IVF and I've seen a few other a ladies in IVF groups that have the same diagnosis, but their husbands were only carriers and didn't have the disease.  B). Be warned that it's very possible to have a false positive on newborn screenings.  My daughter oddly enough had a false positive for the disease I'm a carrier for, but not for CF which she is a carrier for as well.  A family friend have a false positive for CF from just her baby being a carrier.  So if you do go with this donor, don't worry if there is a flagged newborn screening, as long as your husband's genetics are fine, it's practically impossible that your baby would have CF.  [/quote]

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