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[quote=Anonymous][quote=Anonymous]So the way it was explained to me is that it's a good protocol for ladies that are poor responders/DOR in that it might give a better response and can avoid over-suppression that might happen with the antagonist protocol. I did antagonist my first cycle and got canceled with 4 follicles after day 11 of stims which was surprising since my AMH was a tiny bit low but not crazy low. Long Lupron was another protocol that was suggested for me. I'm not sure how it'll go but willing to try something different. Just waiting for CD1 so I can start my 2nd cycle. Here's a page I think explains the long lupron and microflare pretty well-https://www.advancedfertility.com/ivf-low-response.htm[/quote] Lupron has totally opposite effects depending on how it's used. In a long lupron protocol it suppresses follicle development. In Lupron flare, it increases FSH levels to stimulate follicle development. The Lupron stop or micro-dose protocols are also suppressive, but less so than long lupron. You wouldn't generally use long lupron for DOR/poor response. Estrogen priming is another good DOR protocol that is often used. Whether one works better than the other can often depend on the person. I did well with estrogen priming (lots of eggs, but not good quality, so no success), but lupron stop was dismal. Cornell also uses a min-IVF-like protocol and says they typically get close to the same # of eggs as a more standard DOR protocol. I think the idea is that the very high doses of stims aren't good for egg quality, so perhaps its more relevant for DOR with AMA. If you're young egg quality tends to be better even if you have DOR.[/quote]
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