Reply to Mayim Bialik's horrific experience on GLP-1's

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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]I mean, maybe I'm older than most of y'all, but in decades past, the horror stories were always out there about weight loss drugs. Because of the old drugs, I will not take any of the new drugs. [/quote]

Would you take a two-decade old diabetes drug? What about a new diabetes drug? These weren't even developed for weight loss. Weight loss was discovered after those taking it for diabetes were dropping weight. [/quote]

And thus I, who does not have diabetes, would rather wait until it's been used safely on people like me for that period of time at the weight loss dosage.[/quote]

Same. I'm not overweight nor diabetic and have no need to be a guinea pig.  Would be nice if there was a wonder drug, but there's a lot we don't know yet about long term usage.[/quote]
Many of these people are finally skinny "effortlessly", they will withstand nausea, vomiting, sulphur burps, diarrhea, etc, etc. You can't pry that needle or pill from their bony little hands. The overseeing entity (usda?) will have to issue a ban on these drugs for their population and remove them to get them to stop....unless gastric cancers or dehydration/heart issues stops them first. See also: fen phen.[/quote]

Not only the drugs but the gastric bypass and bands didn't work either. Bodies adapt and we'll likely see this with the drugs over time. Then we'll be on to the next craze.[/quote]
My friend got a gastric sleeve in Tijuana. She lost 20 pounds in the first 3 months. She began consuming milk shakes, ice cream and other calorie laden foods which overrode her surgery. Within a year of her surgery, she basically stretched her stomach back out (or something), resumed her previous overeating habits, regained the weight lost and added 20 pounds more. Moral: people will do anything, other than address the core reasons for their overeating (which is evidenced by their relentless "food noise") to lose weight. Sadly, without significant habit changes, lifestyle changes and psychological growth, the WEIGHT ALWAYS COMES BACK.[/quote]

Weight virtually always comes back regardless of lifestyle changes. 90-95% who have lost significant weight gain all or more than all of it back within 5 years. [/quote]

This. If I'm going to lose and regain all my weight, I'd rather do it through healthy eating than deal with the side effects and mess up my GI system.[/quote]

Or you could do it in a more effective way that takes less effort, has a way higher level of success, and for 50% of people has 0 side effects. I’m not pushing GLP-1s at all (I don’t care how you do or don’t lose weight), but most people experience no side effects at all, and the vast majority experience only mild side effects. I for one have experienced plenty of side effects from natural weight loss, including dizziness, brain fog, fatigue, coldness, and decreased sex drive.[/quote]

Claiming that most people have zero side effects on GLP-1s is not supported by current studies. Most suggest the opposite (with varying rates of occurrence and levels of severity). Side effects and cost are also the reasons most commonly given for most people stopping GLP-1s at about the one-year mark.

Aside from rarer, more severe adverse effects, also concerning is that, according to a recent study in[i] The British Medical Journal,[/i] people who come off GLP-1 drugs regain weight four times faster than (behavior-based) dieters.

Most of us understand that these drugs are helping to resolve an intractable health issue for millions, and additionally may be shown to have other substantial benefits. But downplaying or distorting the current scientific understanding of their risks and downsides is unhelpful, and likely has the opposite of your intended effect.
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It's a temporary fix, but like everything else will not be sustainable over the long run.  If it sounds too good to be true it probably is. [/quote]

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