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Expectant and Postpartum Moms
Reply to "Husband has Sickle Cell gene and didn't tell me"
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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]Being a sickle cell carrier lends an advantage - it's protective against malaria (that's why lots of black people have the gene -- the gene helped carriers survive in africa for a long time). having sickle cell requires two parents, so your children will be fine (and will actually have an advantage). https://www.reddit.com/r/DebateEvolution/comments/1gfav0r/the_argument_over_sickle_cell/[/quote] I don’t know about this based on personal experience. I am a sickle cell carrier and got malaria while traveling in the DR Congo. It was severe. I had to be hospitalized. It ruined my trip. Worst time of my life.[/quote] It’s definitely not foolproof. It depends on what genotype you have. There’s different forms of sickle cell. The AA genotype is the typical genotype (no sickle cell trait or disease). It offers no protection against malaria. The AS (means you have sickle cell trait) and AC (means you have Hemoglobin C trait), and CC (means you have Hemoglobin C disease) genotypes are shown to be protective against malaria and have the lowest mortality (death) rates when infected with malaria. The SS (means you have the extreme and most common form of sickle cell disease) and SC (means you have a milder and less common form of sickle cell disease) genotypes are shown to be somewhat protective but also have the highest mortality (death) rates when infected with malaria.[/quote] I’m AS. I just have plain ol’ sickle cell trait.[/quote]
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