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Kids With Special Needs and Disabilities
Reply to "School thinks DS has ASD, dev ped does not agree. Now what?"
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[quote=Anonymous][quote=Anonymous]From page 23: Information on final diagnosis was available for 584 children (97% of included children, 87% male) on electronic medical records. For detection of autism versus non-spectrum disorders, the [b]sensitivity was 67[/b]–91% for communication and social domain scores and 82–94% for social affective and repetitive restricted behaviour domain scores. S[b]pecificity was 65–[/b]95% [b]and 55[/b]–81% respectively. [b]For detection of autism spectrum disorders other than autism versus non-spectrum disorders the sensitivity was 75[/b]–94% for communication and social domain scores and 72–100% for social affective and repetitive restricted behaviour domain scores. [b]Specificity was 29[/b]–81% and[b] 29–[/b]60% respectively. Look at those low ranges, and tell me this is the be-all, end-all test.[/quote] And right below the previous graph is this reminder: This evidence is consistent with the recommendation in NICE CG128 that diagnosis should not rely solely on 1 tool. And from page 25: The authors noted that the best strategy was using the ADI-R clinical cut-off score and the ADOS together, which had sensitivity of 90–98% and specificity of 80–92% across the groups of children analysed. S[b]ensitivity for detecting autism was best when either ADI-R or ADOS were used with sensitivity of 99–100%, but specificity was lower at 45–85%. [/b]If a child’s ADI-R and ADOS scores were both judged to be in the range of concern, the odds ratio of having a best estimate clinical diagnosis of autism was 56.19 (p<0.001).[/quote]
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