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Reply to "Excellent NYT piece about shaming people to take Ozempic, etc for weight loss"
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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]I’m not shaming anyone for taking these drugs! I’m just worried that we don’t know enough about the side effects long term. [/quote] They have been on the market for many years for diabetics. They’re pretty well understood at this point. [/quote] That’s the problem - for diabetes or serious obesity, yeah, the risk of long term side effects may be comparatively less important. The worry is when people start taking them to get down to a BMI of 19. And also the rebound for people who cannot tolerate them. [/quote] Okay. What long term side effects in the population are you referring to that are comparatively less important? Specifically [/quote] It’s a risk-benefit calculation obviously. [/quote] Yes. My question is which risks SPECIFICALLY are you worried about drawing from the data of populations that have already been on the drug many years. [/quote] Fen-phen was also on the market for years. Like all new medications, we won’t know until we know. The rebound effect seems pretty clearly established though. [/quote] The first Fen-Phen study was published in 1992. It never received FDA approval for obesity. It was banned by 1997. [/quote] A minute of googling yeilds a fen-phen paper from 1984: https://jamanetwork.com/journals/jamainternalmedicine/article-abstract/604539 Obviously they are completely different drugs, but there is ample reason to be concerned. [/quote] There is whatever reasons to be concerned that you can identify in the copious high quality data we have. What are your specific reasons?[/quote] My specific reasons are that Ozempic already has a long list of known side effects and we have *no idea* what will happen with long term use in non-diabetics. You’d frankly have to be an idiot to pretend it’s all sunshine and roses. [/quote] Stay mad[/quote]
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