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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]Is it absolutely certain that pfizer will give 5-11 yr olds 10 mcg? Or is it a good chance they will stick with the 30mcg dose like for everyone else so far? Because there is so much more data for that dose?  Has there been any evidence that the 5-11 yr olds already in the trial who got the 30 mcg did poorly? I thought the myocarditis was just in older than 12yr old boys?  [/quote]

We don't have data for younger kids yet.  But for older individuals, yes, the 12-17 year-old-boy demographic had the highest observed frequency of myocarditis and pericarditis, estimated at &lt;70 cases per million second doses.  Though, that should probably be taken with a grain of salt.  When the VRBPAC discussed this, they noted that it doesn't take much to come back with a finding of myocarditis if you go out looking for one.  So, if they looked harder for it in kids, of course they'd find a lot more there.

And yes, the Pfizer phase 2/3 trials used 10mcg in the 5-11 group, and 3mcg in the &lt;5 group.  [/quote]

nobody was “looking” for the myocarditis - these kids were presenting with chest pain to the ER. And we have no idea what the long-term impacts are of it. [/quote]

Really?  I've gone to the doctor before with chest pain.  Do you know how often I've gotten a cardiac MRI?  Never.  Most cases would never get diagnosed.  But they started doing more cardiac MRIs when reports of myocarditis started coming out, and the cardiac MRI is a much more sensitive instrument than an ECG or echo, or just trying to diagnose off of symptoms.

And while it is technically true that we don't know what the long-term impacts are, that's a very different statement than saying we have reason to actually be worried about long-term impacts.

[/quote]

these were young kids presenting to the ER with unexplained chest pain. I’m not sure they were all dx’ed via an MRI but it absurd to argue that the myodcarditis was some kind of incidental finding.

and of course there’s reason to be concerned about long-term impact. you only have one heart! [/quote]

"Concern" can be vastly different things.

I'm sure you could find plenty of scientists that were "concerned" by the NTP study finding an potential association between cancer and exposure to high level of RFR in rats.  And they would say it warrants further research.  What most credible scientists wouldn't say, however, is that in the interim it would be reasonable to shut down wifi or cell towers, or stop the deployment of 5G.

So sure, if that's what you mean by concerned, then absolutely.  We should definitely follow cases of myocarditis to see what happens over time.  But for now, there's no reason to think there will be a lasting impact in the vast majority of cases.[/quote]

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