Reply to PICSI for Male Factor - posting in case this helps someone

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[quote=shibes219]Hi All - I wanted to post the results of my latest PICSI cycle in case it helps someone else.  I know I was trolling this discussion board and others for advice and didn't see too much written on PICSI.  So we have a severe male factor due most likely to undescended testicle as a kid and varicocele veins.  Our first IVF cycle we did ICSI - had 12 perfect 3 day embryos, but by day 5 we only had 1 blast that was BB, and then one that caught up on day 6 and made it to freeze - both BFN.  The hypothesis was that it was the sperm since the embryonic genome takes over embryo development more at day 3.

My husband had a varicocele surgery which improved his motility and morphology a bit (3-4% morph and like 45-60% motility).  Count actually went down from 2m to 1.4m.  So next cycle we tried PICSI to try and pick better sperm.  I did absolutely nothing different on my part.  Unfortunately - I started to ovulate before retrieval so we ended up getting only 10 fertilized eggs.  The 5 day report came yesterday and I was more nervous than waiting for beta results!  5 blasts - three of which were hatching and excellent quality and two of which were still growing.  Then 2 others that were in the stage before blast.  I imagine this was a combination of the PICSI and his surgery, but I credit the PICSI more since his numbers didn't change that much after the surgery.  We're in the TWW now with a perfect fully hatched blast transferred yesterday - praying that this is the one for us!  If you are in a similar situation with a severe male factor - I encourage you to ask about PICSI.  At SG it doesn't cost anything extra.  Good luck and hope this helps someone reading![/quote]

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