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Infertility Support and Discussion
Reply to "Why are high stims bad for low ovarian reserve? "
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[quote=Anonymous][quote=Anonymous]This is still being studied but I believe the current theory is that anti-Mullerian hormone (AMH), LH, testosterone, and E2 are significantly higher in follicles from a natural cycle than in stimulated IVF follicles whereas FSH is significantly lower. This suggests an alteration of the follicular metabolism in stimulated cycles. Here's a paper that compared hormone levels in the follicular fluid from NC-IVF and conventional IVF http://www.ncbi.nlm.nih.gov/pubmed/24608520 However, here is a paper that compared the number of live births from women under 35 who had normal ovarian reserves and it found no difference between mild stimulation and conventional stimulation. http://www.ncbi.nlm.nih.gov/pubmed/26524799 [/quote] So to me, the takeaway based on current research is why use high doses if natural IVF or lower doses yield similar results?[/quote]
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