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[quote=Anonymous]We were planning to do a FET after PGD, but the lab completely screwed up.  Apparently there was something wrong with one of the chemicals, and they weren't able to get any results at all.  I'm 41, husband is 43, no problems other than advanced maternal age.  Our first IVF ended with a trisomy.  This was IVF #2.  We are very scared of multiples, so we wanted to do a single embryo transfer, and for that reason we really needed this PGD.  After the first IVF failed I spent three months pounding down the COQ10 and going to acupuncture faithfully.  I was so relieved when we got 4 embryos.  I thought, now I've done everything I could do, and in a few weeks we'll know for sure.  Well, so much for trying to be in control.

So now our options are either to do a RE-BIOPSY, which would mean thawing the embryos for 24 hours, taking another biopsy and rushing the test in time for us to do a transfer the next day, and refreezing any extra normal embryos.  But in addition to the stress of the extra thaw and refreeze, there's a possibility that the embryos could "overdevelop" to the point where they already start hatching and can no longer implant.  I don't see how this can be a good idea.  I feel that right now the embryos are safe, and although we have lost information, there has been no material damage.  We are basically in the situation of anyone who didn't do a PGD.  But doing a re-biopsy could actually damage the embryos.

But the other option is to transfer without biopsy, which could mean miscarriage after miscarriage.  If none of them are normal, we might be looking at a year spent having miscarriages, after which it would probably be too late to try another IVF, as I doubt I would have any good eggs left at that point.

This experience has really rattled me.  Up until now, I was handling all of this with equanimity.  Any advice or thoughts would be greatly appreciated.[/quote]

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