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[quote=Anonymous]6:55 again - Just wanted to encourage you to think about doing PGD before you move on to immune theory, if you decide to go that route.

So, I'm 43 now, but at 42 I'd had eight miscarriages (starting at 37). No known cause. I got pregnant every month we tried without assistance. Each time - miscarriage. We finally did a round of IVF with a technique called preimplantation genetic diagnosis. PGD is where the doctors actually look at the embyro's DNA to determine if they are good or not instead of what they normally do, which is just look at them and give them a grade. In our case, using the standard eyeball test our embryo's looked great - all top grade. In fact, all of our embryos made it all the way to day 5. We didn't lose one! But the PGD showed that all of our embyros were positive for multiple genetic disorders that were totally incompatible with life.

The lesson I learned from this is that REs do us a great disservice when they tell us our embryos are "top grade" or whatever. You don't know if you have good embyros until you actually test their DNA. All you can know from the eyeball test are which ones are totally falling apart and which ones aren't. Genetically abnormal embyros can look perfectly fine though. So when the RE tells you your embryos look fine or are "top grade," all he or she is saying is that they are not falling apart. That does not mean they are fine and it certainly does not mean they are good enough to result in a healthy baby. Yet, from what I read on this board, this is how a lot of women are interpreting these statements.

For my part, although the PGD cost us an extra $5,000, it was totally worth it. It finally gave us the true cause of our infertility and it made me feel a lot more confident about moving ahead with choices that could and would give us a family. Until that point I was terribly conflicted, primarily about immune treatment. I really did wonder if I should pursue it. But when I saw those DNA results I was able to finally put all that to rest because we had identified a cause. I strongly urge you to consider PGD before you move on to any other treatments because at least it will allow you to know FOR SURE if your embryos are or are not the cause of your infertility.

Good luck.[/quote]

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