Reply to Would you move to IVF after terminating for chromosomal abnormality (T13)?

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[quote=Anonymous]Deciding on next steps and looking for advice. I (38F) have a daughter who just turned 3. She was born right before I turned 36 and was conceived naturally after being treated for an ectopic. Husband and I started trying for a second in fall of 2022, no luck until about a year later when we conceived in October 2023 on our second round of IUI. We had decided in advance that if three IUIs didn't work we would move on to IVF. So we were overjoyed when I got pregnant. Unfortunately we got abnormal NIPT results and confirmed via amniocentesis that the baby had full Trisomy 13. I had a D&E two weeks ago at 17 weeks.

In the immediate aftermath it seemed obvious that when I was cleared to try again we should go straight to IVF with PGT to avoid this happening again. Now that the dust has settled and I'm feeling a bit calmer, I wonder if it's worth trying IUI again. The more I think about the cost, time, and impact on my body, the less certain I feel about IVF. I understand that IVF can take a very long time and involve long periods of waiting, which I know will cause enormous stress. Part of me thinks maybe we should "roll the dice" again with IUI since we know I can get pregnant. And plenty of people have healthy babies after having to TFMR. But I turn 39 soon and if we were to have another trisomy pregnancy, I'd be heartbroken - and it'll set us back many months.

I feel like I know what the answer is and I'm just resisting it. What would you do? Alternatively, have you gone through a TFMR and then had a healthy subsequent pregnancy at advanced maternal age? I'd love to hear your story. [/quote]

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