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Reply to "Zoladex or Lupron"
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[quote=Anonymous]I’ve been on tamoxifen alone, tamoxifen+zoladex, letrozole +zoladex, and letrozole + lupron. I got the moodiness, horrible hot flashes, poor sleep, and fatigue from tamoxifen. I still have some fatigue and poor sleep on letrozole, but less moodiness. The joint pain has been worse on the letrozole. There hasn’t been a huge difference for me between the zoladex and lupron. I only switched to lupron because my oncologist couldn’t get the zoladex in 3 month injections rather than 1 month ones. Zoladex is injected in the fatty area in your lower abdomen. Lupron goes into the hip/glute area. All of the options have been equally hard on my metabolism, and it’s nearly impossible for me to lose weight. [/quote]
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