Reply to Parents of newborns- how are you approaching RSV?

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[quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous][quote=Anonymous]I don't have a newborn currently, but when DS was born at 32 weeks, he received a vaccine for RSV for preemies.

I'm not sure why it's not given out to all newborns, maybe you can ask your pediatrician.

Also, clinical studies have just shown that a new vaccine given to pregnant mothers protects their newborns against RSV. It's not available right now, but it's something to follow.

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It's 10k and only available to premies. [/quote]

This is one of the things I hate most about the USA: life-saving meds exist, but the government is too weak to force pharmaceutical companies to lower their prices, like the European Union and other countries do. Same for the life-saving progesterone injection to prevent pre-term labor. Same for insulin.

It's an outrage.

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It isn’t even available to 32 weekers any more. No evidence that it improves outcomes unless the preemie is born before 28 weeks. So that is what insurance companies cover now. [/quote]
https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/makena-hydroxyprogesterone-caproate-injection-information

It didn’t do anything, has some bad side effects, and was super expensive. 
Also, the progesterone was a big disaster. It just got pulled. [/quote]

Only one progesterone got pulled, the others work. I was one of the lucky recipient of progesterone injections back in the day, and so was my mother. Otherwise I'd have died as a micro-preemie, and my kid would have too. The RSV vaccine works.[/quote]

Have you actually looked at the data?  Synagis barely moves the needle.

Progesterone has zero evidence of working. That was the whole thing with Makena. Pre-Makena, it was prescribed off-label with no data to support it. Then the poorly run Makena trial. Then it got sold. They had to do post-approval surveillance and the data was not good.

It doesn’t get prescribed very often now. Little benefit and lots of potential issues. [/quote]

Here is the Synagis statement from the AAP https://publications.aap.org/pediatrics/article/134/2/415/33013/Updated-Guidance-for-Palivizumab-Prophylaxis-Among?autologincheck=redirected?nfToken=00000000-0000-0000-0000-000000000000

Benefit for 28 weekers and younger. [/quote]

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